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FDA approval of metformin for diabetes does not mean FDA approval for longevity use - those are distinct regulatory determinations, and the longevity indication is off-label

But they do basically the same thing

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Susantitaphong P., Cruz D.N., Cerda J., Abulfaraj M., Alqahtani F., Koulouridis I., Jaber B.L., Acute Kidney Injury Advisory Group of the American Society of, N World incidence of AKI: A meta-analysis