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doi: 10.3389/fnmol.2018.00467 Received 27 August 2018 Accepted 03 December 2018 Published 18 December 2018 Volume 11 - 2018 Edited by Karsten Hiller, Technische Universitat Braunschweig, Germany Reviewed by Dietmar Fuchs, Innsbruck Medical University, Austria