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Transepidermal water loss (TEWL) measurements in rosacea skin are consistently elevated compared to healthy controls, indicating that the barrier is already operating in a compromised state

The mouse was generated by CRISPRCas9 technology to remove exons 24, resulting in frameshift and protein reading frame premature termination, the genotyping primers are: forward primer, 5-TGCTGCCGTCATTTTCTGCCTCAT-3