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They are part of a medical approach to weight management for people struggling with obesity, insulin resistance, metabolic health concerns, appetite control, weight regain, or difficulty maintaining results

The table lists mild to moderate nausea in 40-50% of people as the expected gastrointestinal adjustment, and attributes the variation to gastric emptying rate, GIP receptor pathway sensitivity, and prior gastrointestinal tolerance

Collins MK, Choudhary S, Ho J, Bunimovich YL

The study visits included screening, baseline, 6, 10, and 14 weeks

Nevertheless, the calorie deficit remains the foundational mechanism through which weight loss occurs, regardless of the dietary approach used to achieve it