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For instance, a study on ME/CFS demonstrated the efficacy of the tricarboxylic acid (TCA) cycle metabolite oxaloacetate in improving symptoms (Cash and Kaufman, 2023), patients showed marked improvements in fatigue scores as measured by the Chalder Fatigue Questionnaire in a randomized, double-blind, placebo-controlled trial using AXA1125

10.3748/wjg.v12.i9.1329 106

Both neurogenic inflammation and oxidative stress are key factors in migraine development, and topiramates neuroprotective potential through its anti-inflammatory and antioxidative effects is noted

2018 Sep 25;9(1):3923

Clumping or stickiness typically indicates moisture absorption