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Can GLP-1 Agonists Be Given Along with Intermittent Fasting

The FDA approved Wegovy, the first GLP-1 exclusively for weight loss, in 2021, and in the past five years, prescriptions for this class of drugs have more than quadrupled

Bottom line: Pioglitazone is an insulin-sensitizing TZD that often causes weight gain, while GLP-1 agonists are hormone mimetics that typically support weight loss

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A modest but significant reduction in HbA 1c and the risk of total and nocturnal hypoglycaemia has been observed for basal insulin analogues vs NPH insulin [210]