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When phentermine and topiramate were co-administered to rats at doses of 3.75 and 25 mg/kg, respectively [approximately 2 times the maximum recommended human dose (MRHD) based on area under the curve (AUC)], or at the same dose to rabbits (approximately 0.1 times and 1 time, respectively, the clinical exposures at the MRHD based on AUC), there were no drug-related malformations

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Gentle daily activity supports energy expenditure and helps with constipation

These advanced medications support weight loss by helping you feel fuller for longer, eat less, and burn fat more efficiently

However, if your levels are only slightly low, the changes may be more subtle, showing up as better endurance during your workouts or improved focus at work