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It is found in nearly every cell and is essential for protecting tissues from oxidative stress, which is the damage caused by unstable molecules called free radicals

It blocks the degradation of inhibitor of kappa B (IB) kinase, thereby inhibiting the activation of transcription factors such as NF-B and modulating the cellular inflammatory response (Pastorino et al., 2018

USP20 enhances the stability of SLC7A11 by deubiquitinating the K48-linked polyubiquitin chains at the K30 and K37 residues of the SLC7A11 protein

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Toutefois, des concentrations leves de cuivre libre pourraient thoriquement induire un stress oxydatif