Moreover, 5 randomized clinical trials (RCTs) with cardiovascular outcomes have shown the cardiovascular and renal benefits of some drugs in the GLP1-RA class (liraglutide, semaglutide, albiglutide, dulaglutide, efpeglenatide) in subjects with T2D at high cardiovascular risk [55], which could also extend to subjects with prediabetes
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Building and maintaining muscle through strength training shifts that ratio toward fat loss, which improves both body composition and metabolic rate
Patients struggling with obesity and concurrent smoking addiction, depression, or emotional eating, should begin treatment with centrally acting medication such as naltrexone/bupropion or phentermine/topiramate (119, 121)