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Outcome measures include frailty status using Fried criteria and Frailty Index accumulation of deficit, selected frailty biomarkers (interleukin-6, tumor necrosis factor-alpha, and insulin-like growth factor-1), physical function, cognitive function, nutritional status and biochemical profile

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This decline is a major contributor to issues like: Loss of muscle mass Increased body fat Reduced energy and stamina Decreased libido and sexual function Weaker bones Thinning skin and hair Impaired mental clarity and mood The good news