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The primary objective of the study, conducted in 300 people with type 2 diabetes, was to evaluate whether GIP/GLP-1 RA, dosed once weekly, was superior to placebo in reducing HbA1c from baseline at 26 weeks

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maximum one dose per 24 hours and 8 doses per month

Researchers considering retatrutide should be aware of this potential effect and monitor for unusual skin sensations during dose escalation

Particular attention has focused on dermal papilla cells, specialized structures located at the base of hair follicles that help regulate growth cycles