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Die Pharmazie-an International Journal of Pharmaceutical Sciences 58(10):753755 Panda S, Kar A (2006) Evaluation of the antithyroid, antioxidative and antihyperglycemic activity of scopoletin from Aegle marmelos leaves in hyperthyroid rats

[PUBMED Abstract] Uren RF, Howman-Giles R, Thompson JF, et al.: Lymphoscintigraphy to identify sentinel lymph nodes in patients with melanoma

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An invasive approach includes delivery of medication directly to the brain through injection/surgical implants or disruption of the tight endothelial junction of the BBB to facilitate drug penetration

Their benefits, however, depend on the context, the quality of the extracts used, and potential contraindications, hence the importance of considering them as targeted support, rather than a "detox" miracle solution