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They represent thousands of people dealing with a problem that goes far beyond simple discomfort

G6PD deficiency (G6PD-d) is the most common enzymopathy in the world, with approximately 500 million affected people worldwide

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Further mechanistic studies suggest that the cardioprotective effects of APS may be mediated by the regulation of the PI3K/Akt/mTOR signaling pathway, which is essential for maintaining cardiomyocyte survival, regulating autophagy, and inhibiting apoptosis ( 60 Co- irradiation in mice, achieving its protective effect by promoting the secretion of IFN- and interleukin-4 (IL-4) (Zhao et al., 2015)

Seregina T, Shakulov R, Shatalin K, et al