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The ability of the decreased CYP2E1 to suppress APAP-induced hepatotoxicity was previously reported by CYP2E1 knockout mice, indicating that CYP2E1 is the key enzyme responsible for the metabolic conversion of APAP into the active hepatotoxic NAPQI

however, as with any medication, some individuals may experience side effects

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Injection site irritation, mild headaches, fatigue, or flushing during the first one to two weeks are generally manageable and often resolve as the body adjusts

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