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According to recently published clinical research by Galderma in January 2025, patients using GLP-1 medications frequently report significant facial alterations: Loss of facial volume creating shadowing and hollowness Increased skin laxity and sagging Changes in facial structure and balance Skin appearing less radiant and drier An overall aged appearance beyond their chronological age Dr

Weight loss plateaus despite maximum dose, since tirzepatide's dual mechanism may overcome semaglutide resistance

Importantly, these medications are not recommended for patients with severe gastrointestinal disease, including gastroparesis, due to their effects on gastric emptying

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