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This assessment also explores underlying conditions such as insulin resistance, sleep apnea, thyroid abnormalities, hypertension, and mood related eating patterns

Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age

For users who want the simplest possible approach, a multivitamin combined with a protein supplement and fiber covers the absolute basics