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Side effects are generally mild and rare but can include temporary flushing, a metallic taste, or minor injection site discomfort
The brain, due to its high metabolic activity, is especially susceptible to oxidative stress, and its natural defense mechanisms, like antioxidant enzyme systems, are often inadequate in these diseases
Exogenous Verses Endogenous Antioxidants Antioxidants can be made by the body (endogenous) or need to be consumed through the diet (exogenous) as the body cannot make them
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Thus, amount of transcutol p preferably from 0.5 - 10, more preferably from 1 to 8 % and most preferably from 2 - 6 % is found to provide at least 40 - 80 % release in 12 hrs for lower doses
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