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Description

Autonomic changes in ME/CFS are likely to cause an overall effect of vasoconstriction and resultant hypoperfusion (58), which is central to the pathology of ME/CFS (183) ( Figure 8 )

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L-cells are of the open type with apical processes extending towards the gut lumen with secretory granules in the basolateral pole where they can be released and their secretory material enter capillaries

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