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mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion

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The biofilm-infected microenvironment (BIM), which orchestrates macrophage metabolic reprogramming by downregulating FAO and LDs biogenesis, is an important factor contributing to this process, thereby skewing macrophages toward the immunosuppressive M2 phenotype and attenuating antibacterial immunity

Early improvements, such as smoother texture and more even tone, often appear by the end of this initial period

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