Outcome measures include frailty status using Fried criteria and Frailty Index accumulation of deficit, selected frailty biomarkers (interleukin-6, tumor necrosis factor-alpha, and insulin-like growth factor-1), physical function, cognitive function, nutritional status and biochemical profile
This prospective observational cohort study received approval from the Institutional Review Board (IRB) of the Federal University of Minas Gerais (UFMG) (CAAE3768820.1.0000.5149)
Fitzgerald et al., 2022
Presentation 2: Safety, Tolerability, PK, and Efficacy of MET-097A Next-generation Nutrient-stimulated Hormone Peptide Analog for Chronic Weight Management Trial Design The study was a randomized, double-blind, placebo-controlled Phase I trial conducted at a single site (NCT06857617)
2022 Oct 3;132(19):e152341