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Even if virtually, all cell types synthesize GSH, the main source of the tripeptide is liver where the bulk of cysteine, the rate limiting amino acid, derived from diet is metabolized

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Since the ultimate goal of the project was to produce a clinically relevant molecule that could be delivered peripherally but still exhibit pro-cognitive/anti-dementia activity, the effectiveness of both the intraperitoneal and oral delivery routes of dihexa administration were determined using the scopolamine model

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