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During 12-day induction, no pluripotency gene expression ( Oct4, Sox2, and Nanog ), immature HB markers, and HPC markers were detected, suggesting that the conversion of MEFs to iHeps bypassed the intermediate stem cell stage (Zhong et al., 2024)

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[9] Active site [edit] The active site of catalase-peroxidase generally includes one tryptophan, two histidines, one arginine, and the heme b iron ligand, coordinated through histidine residues