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Finasteride selectively inhibits Type II 5-alpha reductase

Supplemental folic acid use at the higher end of this suggested range has been recommended by some in order to ensure a minimum RBC folate concentration of 906 nmol/L (32) after four weeks of supplementation (30, 33), which would maximize NTD risk reduction particularly for those with low folate status

It actively binds to growth factor receptors including VEGFR-2 and modulates nitric oxide pathways that control vasodilation and angiogenesis

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