Most of the mature cathelicidins are linear peptides that adopt an -helical fold with an amphipathic character when exposed to hydrophobic environments (e.g., biological membranes), but -sheet structures stabilized by disulfide bonds, loop structures or extended polyproline structures are also known [104]
Homology with the protein disulfide isomerase (PDI gene product) of other organisms
The peptide exhibits anti-inflammatory properties by modulating cytokine production, reducing excessive inflammatory mediators like TNF- and IL-6 while supporting resolution of inflammation and transition to tissue repair phases
This treatment is particularly noted for its versatility,being effective on various body areas such as the chin, jowls, back fat, andlove handles
Fang J, Wang L, Wu T, Yang C, Gao L, Cai H, et al