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A recent meta-analysis of RCTs reported improvements in several metabolic parameters, including markers of glycemic control, insulin sensitivity, and lipid metabolism, demonstrating that targeted modulation of the gut ecosystem can shift clinically relevant endpoints in humans (140)

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Given the increasing interest in the GLP-1 target, we downloaded clinical trial data for ~3,800 GLP-1 related studies through July 2024 and asked, what other conditions are GLP-1 modulating drugs being tested for

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