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In clinical trials, non-diabetic individuals taking semaglutide experienced significant weight loss, with average weight loss ranging from 10% to 15% of initial body weight over 6-12 months of treatment

Martinez de Morentin PB, Gonzalez-Garcia I, Martins L, Lage R, Fernandez-Mallo D, Martinez-Sanchez N, Ruiz-Pino F, Liu J, Morgan DA, Pinilla L, Gallego R, Saha AK, Kalsbeek A, Fliers E, Bisschop PH, Dieguez C, Nogueiras R, Rahmouni K, Tena-Sempere M, Lopez M

Most clinical trials have shown it is well accepted by most patients and the side effects have mostly been negligible and very few have occurred

Clinical trial data demonstrates that Wegovy pill produces significant, sustained weight loss when combined with lifestyle modifications like a reduced-calorie diet and increased physical activity