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*Total Microbial Count

2019;10(10):e00078

For multi-dose vials where the stopper is punctured multiple times over days or weeks, distilled water lacks the benzyl alcohol preservative that prevents bacterial contamination microbial growth begins within 2448 hours, producing endotoxins that interfere with research outcomes and cause injection-site reactions

PLoS One 11 , e0149296 (2016)

Similarly, in 2017, DOD introduced a regulation that requires all vendors who do business with the department to more safely guard covered defense information that is transmitted to or stored in their systems or networks for contracted work