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While semaglutide works mainly on blood sugar and appetite, it can also have effects on the brain, especially in areas related to hunger and reward

A collection of POEMs published in AFP is available at Copyright 2026 by the American Academy of Family Physicians

These effects lead to fewer calories being consumed and, over time, significant weight loss

Erika Di Zazzo, University of Molise, Italy Updates Copyright 2021 Feng, Barb, Allen, Regan and Saligan

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