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The translocated AIFM1MIF complex then translocates back to the nucleus, where it contributes to chromatin condensation and DNA fragmentation, ultimately resulting in parthanatos-mediated cell death [154]

Alternatively, inflammation may have been below detection thresholds in a subset

Carnitine deficiency Carnitine deficiency can lead to many problems such as muscle weakness, fatigue, problems with heart (such as heart enlargement), liver or brain (encephalopathy), confusion etc

Stimulation of renal erythropoietin secretion leading to an increased haematocrit that could favour heart and kidney metabolism through improved oxygen delivery