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Persistent loss of hippocampal neurogenesis and increased cell death following adolescent, but not adult, chronic ethanol exposure

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Proc Natl Acad Sci USA 93 : 1196211967

This protective effect involves TUG1 binding to the RNA splicing factor 1, which stabilizes ACSL4 mRNA- a key driver of lipid peroxidation- highlighting a novel axis for therapeutic intervention