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Tirzepatide (Mounjaro) is a dual agonist targeting GLP-1R and GIPR, and is licensed by the MHRA in the UK

Human studies in this area are limited by small sample size and often nonrandomized character

In addition to nephrotoxicity and hepatotoxicity, numerous studies have documented gastrointestinal toxicity associated with EGCG administration, whether by gavage or in diet, in animal models (240242)

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Potential Side Effects That May Affect Your Energy Whilst some patients report increased energy on GLP-1 therapy, others may experience side effects that temporarily reduce energy levels, particularly during the initial treatment phase