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Kidney-targeted delivery of prolyl hydroxylase domain protein 2 small interfering RNA with nanoparticles alleviated renal ischemia/reperfusion injury

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The GLP-1 agonist TZP has been shown to alleviate cognitive dysfunction caused by diabetes in rats by reducing neuroinflammation, as evidenced by decreased levels of TNF-, IL-6, IL-1, and phosphorylated NF-B, thereby mitigating insulin resistance (Wilson et al., 2020)