Adverse effects observed in trials to date include: Gastrointestinal symptoms nausea, vomiting, diarrhoea, and constipation (common with GLP-1 receptor agonists) Reduced appetite and weight loss , which may be excessive in some individuals Elevated heart rate , a concern noted with glucagon receptor agonism As with other incretin-based therapies, there is also a class-level signal for acute pancreatitis and gallbladder disease (including cholelithiasis and cholecystitis)
A vitamin B12 deficiency is always treated through a therapy with supplements
It emphasizes the importance of verifying each products
Accessed on November 6, 2025 at Reis, G., & Kosmas, C
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