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Enhanced activity of AMP-activated protein kinase (AMPK) and increased expression of PGC-1, NRF-1, and mitochondrial transcription factor A (mtTFA) suggested that mitochondrial biogenesis was stimulated, improving cellular energy balance and reducing oxidative damage in the brain

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described the selection of the C1q specific nanobody C1qNb75 that is able to inhibit activation of the classical pathway (CP) of the complement system (179)

EU approval typically follows FDA approval by 36 months

10.1615/intjmedmushr.v12.i3.70 [DOI] [Google Scholar] Lallawmsanga, Passari A