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N 10 -Formyltetrahydrofolate Synthesis Synthesis of N 10 -formyl-THF (10-formyl-THF) can occur by two distinct pathways, both of which utilize the same multifunctional enzyme encoded by the MTHFD1 gene
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There follows invasion of endovenous trophoblasts into the uterine veins, this enabling, throughout pregnancy, drainage of fluids originating in the placenta back into the maternal circulation
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