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Celebrities and social media have also contributed to their rise in popularity

Discard Zepbound immediately if any of these conditions apply: The pen has been unrefrigerated for more than 30 days Room temperature exceeded 86F (30C) at any point The pen was frozen, even briefly The solution appears cloudy, discolored, or contains particles The pen was exposed to direct sunlight for extended periods The expiration date has passed When in doubt, throw it out

People with higher starting weights often lose more pounds initially, while those with lower starting weights may lose fewer pounds but might notice more significant changes in body composition