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Intense pulsed light (IPL), Low-fluence Q-switched (LFQS) lasers, non-ablative fractional lasers (NAFL), and picosecond lasers are among the most frequently used light and laser-based therapies in melasma management (Hofbauer Parra et al., 2016

In addition to the transcriptional regulation of SLC7A11 under conditions of cell stress, SLC7A11 is also regulated via post-transcriptional mechanisms (5, 32)

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162 Thus, ROS generated by UV exposure can hinder two critical enzymes involved in oxidative DNA damage repair