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Ness utilized a generally accepted protocol and followed Bradford Hills criteria, a respected analysis method

Over the last few decades, therapeutic development of nanomedicine at preclinical stage has shown to progress at a fast pace, thus paving the way for its potential impact on human health in improving prevention, diagnosis, and treatment of age-related neurodegenerative disorders, including AD

Ohno, M

Clinical trials and scoping reviews show promising signalsimproved quality of life and symptom control in some patientsthough larger confirmatory trials are still emerging

In another report, the PEGylation of these nanocarriers loaded with anthocyanins resulted in an enhanced efficacy in the prevention of neurodegenerative disorders such as AD, compared to the uncoated specimen both in vivo and in vitro (Kim et al., 2017)