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1,25-Dihydroxyvitamin D3 prevents toluene diisocyanate-induced airway epithelial barrier disruption

The most frequent side effects are gastrointestinal and include nausea, vomiting, diarrhea, and constipation, typically most pronounced during initial weeks and dose increases

A provider may monitor: Symptoms and side effects Injection-site reactions Sleep quality Appetite changes Fluid retention Blood pressure Glucose or A1C when appropriate IGF-1 when appropriate Recovery response Whether treatment should continue, pause, or change Monitoring helps prevent patients from guessing, overusing, or continuing therapy when symptoms suggest the plan should be adjusted

This action leads to the uptake of caveolin, restoration of mitochondrial function, and inhibition of ROS production

10.3389/fnana.2025.1557961 338 NakhalM