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Increasingly, Afshar is initiating conversations with patients who he says are "not that overweight" but who he thinks could use these drugs to boost their longevity by driving down visceral fat stores and lowering inflammation across the body

Chiu CK et al., J Neurol Sci 2011 High-dose methylcobalamin in ALS

Hypoglycemia is a real risk at doses above 60 mcg, particularly when combined with insulin or during caloric restriction

But even in the same health system, all medical records arent necessarily the same, which means we rely on the patient to provide this information to us