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In preclinical adipocyte models, studies suggest this shift in metabolic flux is associated with changes in lipogenic gene expression, including reduced expression of key adipogenic transcription factors

The implementation of GST genotyping could identify optimal responders who would derive maximum benefit from SFN supplementation (105, 106)

Mitogen-activated protein kinases in cell-cycle control

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The expression levels of CYP4A1 was significantly increased, 17-HSD2 (17 hydroxyl steroid dehydrogenase type 2) was decreased, and CYP4A2 (cytochrome P450 1A2) not statistically changed in ibuprofen treated male livers (Fig