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Results Establishing transgenic zebrafish models for LMNA -related muscular laminopathy To investigate the pathogenesis of LMNA -related muscular laminopathy, we created transgenic zebrafish lines expressing human wild-type LMNA and five LMNA mutants

The test examines key variants including GLP1R rs6923761, GIPR rs1800437, and FTO rs9939609, which directly affect how patients respond to semaglutide versus tirzepatide or combination therapies