NICE guidelines (NG28) recommend reviewing GLP-1 treatment at around 6 months and continuing only if there has been a meaningful reduction in HbA1c (typically at least 11 mmol/mol [1%]) and weight loss of at least 3% of initial body weight
Ann Neurol 48(5):766773 Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Perucca E, Wiebe S et al (2010) Definition of Drug Resistant Epilepsy : Consensus Proposal by the Ad Hoc Task Force of the ILAE Commission on Therapeutic Strategies 51(6):10691077 Lai Q, Li Q, Li X, Wang H, Zhang W, Song X et al (2022) GluR3B antibody was a biomarker for drug-resistant epilepsy in patients with focal to bilateral tonic-clonic seizures
How NAC Works in the Brain (in Simple Terms) Researchers believe NAC helps in three major ways: Boosts Brain Protection: NAC increases glutathione, an antioxidant that protects brain cells from stress and damage[1]
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Glutathione detoxifies reactive metabolites such as N-acetyl-p-benzoquinone imine (NAPQI)