10.3390/antiox11010109 43 HavenaarR
Other contributors include faulty axonal transport, resulting in buildup of neurofilaments and synaptic breakdown (Taylor et al., 2016), and genetic mutationssuch as SOD1 (causing harmful protein accumulation), FUS (interfering with RNA handling), and TBK1 or OPTN (which impair the cell's waste disposal system known as autophagy
These daily habits, combined with targeted MTHFR supplements, create a strong foundation for optimal methylation and detoxification
Additionally, it has been demonstrated that most genes involved in ferroptosis are directly or indirectly regulated by Nrf2 ( 5 Treating depression by inhibiting ferroptosis 5.1 Traditional Chinese medicine 5.1.1 Active ingredients of traditional Chinese medicine Allicin, a prominent active compound in Chinese herbal garlic, has been found to possess neuroprotective effects ( Saikosaponin B2 (SSB2), derived from the Chinese herbal medicine Radix Bupleuri, has a long history of being used to treat depression, as documented in the TCM classic Taiping Huimin HeJiJu Fang (YANG et al., 2017)
Timing Matters: Take these supplements on an empty stomach or as directed for better absorption