It is not pleasant, but it generally resolves as the gut adapts
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In the SURMOUNT-1 trial, which evaluated tirzepatide in adults with obesity without diabetes, diarrhea occurred in approximately 21.2% of participants receiving 5 mg, 19.5% receiving 10 mg, and 23.0% receiving 15 mg weekly, compared to 7.3% in the placebo group
After the procedure, you should notice your upper lip appearing slightly fuller and more defined
In clinical terms, we say it drastically increases gastric motility , meaning your stomach empties its contents into the intestines at hyper-speed, making you feel completely empty and starved