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They help treat different kinds of problems and the benefits can help in aiding the life of the individual largely

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Oxidative Med Cell Longev 2015(1):918426 Piepponen TP, Kiianmaa K, Ahtee L (2002) Effects of ethanol on the accumbal output of dopamine, GABA and glutamate in alcohol-tolerant and alcohol-nontolerant rats

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Indications: Guanethidine is no longer available in the USA due to lack of availability, but is available in the UK (wikipedia) Was used for severe cases of hypertension, either alone or as an adjunct drug Contraindications: Guanethidine can cause a hypertensive crisis in patients with pheochromocytoma due to the release of catecholamines (tyramine like action)