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Post-treatment, the expression of the serotonin reuptake transporter (SERT) significantly increased, while tryptophan hydroxylase-1 (TPH-1) expression significantly decreased in colonic tissue, suggesting exendin-4 mitigates visceral hypersensitivity by upregulating SERT and downregulating TPH-1

Pentadecapeptide BPC 157 Resolves Pringle Maneuver in Rats, Both Ischemia and Reperfusion

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Pugliese GD, Barrea LD, Laudisio DD, et al