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This led to clinical trials for further validation

The question of whether Mounjaro is a GLP-1 receptor agonist is nuanced

B.OlsenJ

Mitapivat-induced changes are not limited to reticulocytes, as suggested by the observed significant reduction of erythrophagocytosis (Figure 4B) and the direct effect of mitapivat on splenic macrophages resulting in a proresolving profile