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Onartuzumab (MetMAb), SAIT301, ABT-700 (h224G11), ARGX-111, and DN30 are specific antibodies against c-Met, preventing the binding of c-Met to HGF [169,170,171]

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Inflammopharmacology 25 (4), 439449

The exemplary mimic, Dihexa, binds to HGF with extraordinary affinity (Figure 43), blocking HGF dimerization (Figure 44), and markedly augments the ability of HGF to signal to c-Met (Figure 45) and initiate cellular responses (as discussed above)

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