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Notably, in STZ-induced T2D mice, LEO intervention not only dose-dependently improved oral glucose tolerance (Figure 1B) but also significantly elevated GLP-1 levels in serum and colonic tissues

This gradual titration schedule helps minimize gastrointestinal side effects while allowing the body to adapt to the medication's effects

maintaining the lowest dose that normalizes TSH mitigates these outcomes

Oral supplements face a tough journey through the digestive system, where only 10-50% of the nutrients may be absorbed

Resistance training preserves lean muscle mass, which keeps metabolic rate higher and improves body composition even when the scale moves slowly